tPA and Ischemic Stroke: Focused Update of 2010 Clinical Practice Advisory from the American
Academy of Emergency Medicine

Reviewed and approved by the AAEM Board of Directors (3/17/2017)

Executive Summary:
No new studies published between 2010 and 2016 meaningfully reduced uncertainty regarding our understanding of the benefits and harms of tPA for acute ischemic stroke. Discussions regarding benefit and harm should occur for patients and risk prediction scores may facilitate or expedite the conversation.

Continue Reading

References and Literature Grading (PDF)